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Bulletin of the chemical society of ethiopia / The Chemical Society of Ethiopia
Titre : Bulletin of the chemical society of ethiopia Type de document : texte imprimé Auteurs : The Chemical Society of Ethiopia, Auteur Editeur : The Chemical Society of Ethiopia Année de publication : Décembre 1987 Importance : 91 p. Format : Grand ISBN/ISSN/EAN : 1011-3924 Note générale : Science et recherche Langues : Anglais Catégories : ANALYSE CHIMIQUE
BIOCHIMIE
RECHERCHE SCIENTIFIQUE
SCIENCES NATURELLESIndex. décimale : 101 SCIENCE ET RECHERCHE Résumé : There has been countinuing interest in the chemistry of transition metal chelates of schiff drived from S-methylhydrazinecarbodithioat(1)(1). The carcinostatic activity of these chelates(2,3) has attracted particular attention for studying the interaction of these molecules with nitrogen donor Lewis bases. This may help in understanding their mode of action in biological systems (4-7). The cytotoxic and antitumor activities (2,8) of this class of chelates may result from their binding to the nucleic bases in DNA or ther similar targets foiming different adducts within the cell. This paper report further investigation of the reaction between square planar bis(ligand)nickel(II) chelates of the type (2); with pyridine (py) and 1,10-phenantroline (phen).
Permalink : http://enda-cremed.org/bpd/opac_css/index.php?lvl=notice_display&id=30873 Bulletin of the chemical society of ethiopia [texte imprimé] / The Chemical Society of Ethiopia, Auteur . - Ethiopie : The Chemical Society of Ethiopia, Décembre 1987 . - 91 p. ; Grand.
ISSN : 1011-3924
Science et recherche
Langues : Anglais
Catégories : ANALYSE CHIMIQUE
BIOCHIMIE
RECHERCHE SCIENTIFIQUE
SCIENCES NATURELLESIndex. décimale : 101 SCIENCE ET RECHERCHE Résumé : There has been countinuing interest in the chemistry of transition metal chelates of schiff drived from S-methylhydrazinecarbodithioat(1)(1). The carcinostatic activity of these chelates(2,3) has attracted particular attention for studying the interaction of these molecules with nitrogen donor Lewis bases. This may help in understanding their mode of action in biological systems (4-7). The cytotoxic and antitumor activities (2,8) of this class of chelates may result from their binding to the nucleic bases in DNA or ther similar targets foiming different adducts within the cell. This paper report further investigation of the reaction between square planar bis(ligand)nickel(II) chelates of the type (2); with pyridine (py) and 1,10-phenantroline (phen).
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